Best 4 Allergy Prevention

Best 4 Adults™ Allergy Prevention

Best 4 Kids™ Allergy Prevention

Note:  Ingredients are common to both products except where specifically indicated otherwise alongside the ingredient name.

BIO-QUERCETIN

What is Bio-Quercetin?

Is made from the seedpods of a Fava d´anta tree (Dimorphandra molis), used in traditional Brazilian medicine as anti-inflammatory and wound-healing treatment. Bio-Quercetin is better bioavailable, biologically active natural form of Quercetin in its most bioavailable form of a glucoside (isoquercitrin). Quercetin is a phytochemical that is part of the colouring found in the skins of apples, red onions, raspberries, red grapes, cherries, and wine. Notice that all of these fruits have dark pigment. It has been said that red wine, for example, is healthier than white wine. This is in part due to the higher flavonoid content. However, Quercetin can also be found in non-red pigmented fruits and veggies such as broccoli, a variety of leafy greens, citrus fruits, and more.

Quercetin’s antioxidant flavonoid has been used for over 30 years to boost resistance to food and respiratory allergies. Its biological effects are mainly due to its antioxidant activity, to a specific synergy with vitamin C (Quercetin and vitamin C protect and regenerate each other) and to wide-ranging, multi-functional anti-inflammatory activity.

Quercetin inhibits production of histamine by stabilizing basophils and mast cells. Histamine is directly responsible for most of the unpleasant symptoms associated with allergies (sneezing, itching, etc). Quercetin is widely used by those who suffer from constant allergies (such as dust) and seasonal allergies (such as hay fever). Quercetin acts directly on the intestinal tract to reduce reactions to dietary allergens.

BROMELAIN

Bromelain is a natural mixture of protein digesting enzymes found in the stem and fruit of the pineapple, a tropical fruit native to Central and South America. Bromelain has been used for hundreds of years in folk medicine as a digestive aid and to treat inflammation and other health problems. Christopher Columbus found pineapples growing on the island of Guadeloupe in 1493 and brought them back to Spain. By the 1600s, they were very popular in Europe. In the sixteenth and seventeenth centuries, the plants were distributed to the Pacific Islands, India, and Africa. Pineapple was first established as a commercial crop in Hawaii in 1885. Recently, Bromelain has been investigated for medical uses, including possible anti-cancer activity. Bromelain acts by a variety of mechanisms to help maintain tissues in a normal state of comfort.

Bromelain has been shown helpful for upper respiratory tract infections such as Sinusitis and Bronchitis. Bromelain helps to reducing nasal inflammation and swelling caused by hay fever and break up the mucus in the nasal, sinus and respiratory areas. It also assists in smooth muscle relaxation.

BUTTERBUR

Bearing the Latin name of "Petasites officinalis" and more commonly known under the names of langwort or butterbur this herb is of perennial type and grows on the fields of Europe, Asia and North America. It can reach considerable sizes; only one leaf can grow as wide as an umbrella. It blooms at the end of April and the roots bearing a finger-like thickness are entwined in an underground net. In Europe, the butterbur has long been known as a medicinal herb. For centuries the herb has been considered as an effective remedy against fever and spasm. The Greek physician Dioscurides - who described the medicinal properties of over six hundred herbs and over a thousand types of narcotics - used the butterbur leaves in treating the skin illnesses. Later in the 14th century the butterbur was used for relieving the effects of the "black death" plague and fever. Native Americans applied butterbur as a remedy for headaches and inflammations. The main usage of the butterbur today is mostly linked to controlling headaches, asthma and allergies. Extracts from the butterbur root are used in the treatment of stomach ulcer, infections and congestions.

Butterbur has anti-inflammatory effects that decrease histamine and leukotriene’s (chemicals involved in allergic reactions). It is thought that butterbur works similarly to antihistamines by blocking the action of the inflammatory chemical histamine, which is released by your immune system during an allergic reaction.

FOLIC ACID

What is Folic Acid?

Folic acid (also known as vitamin B₉ or folacin) and folate (the naturally occurring form), are forms of the water-soluble vitamin B₉. The human body needs folate to synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in biological reactions involving folate. It is especially important during periods of rapid cell division and growth. Children and adults both require folic acid in order to produce healthy red blood cells and prevent anaemia. Folate and folic acid derive their names from the Latin word folium (which means "leaf"). Leafy vegetables are a principal source, although, in Western diets, fortified cereals and bread may be a larger dietary source.

Allergic diseases

There is a relationship between folic acid and allergic diseases. In one study that examined the relationship between serum folate levels and markers of atopy, wheeze, and asthma in 8083 subjects serum folate levels were found to be inversely related to IgE level, atopy, and wheeze in a dose-response relationship. Increased folate levels were also associated with decreased risk of doctor-diagnosed asthma. Folic acid supplementation during late pregnancy is associated with an increased risk of childhood asthma, increased risk of persistent asthma, and poorer respiratory function in young children.

Folic acid also regulates the body’s immune system response to allergens.

FORSLEAN (Adult formulation only)

What is Coleus forskohlii?

Coleus forskohlii is a botanical that has been used since ancient times in Hindu and Ayurvedic traditional medicine. Coleus is the source of a unique substance known as forskolin. It is a perennial member of the mint (Lamiaceae) family and grows in the subtropical temperate climates of India, Nepal, Sri Lanka, and Thailand. Plant height is approximately 1-2 feet and its striking leaves are teardrop shaped, shimmering green framing a bright purple centre; leaf colour varies depending on the amount of shade. A cluster of stalked pale purple or blue flowers branches off a single stem. The rootstock is typically golden brown, thick, fibrous, and radially spreading. The roots are harvested in the fall, when forskolin is at its most concentrated and the colour is the brightest. The root portion of the plant has been traditionally used for medicinal purposes and contains the active constituent, forskolin. Forskolin was named after the Finnish botanist, Forskal. Historically, it has been used to treat hypertension, congestive heart failure, eczema, colic, respiratory disorders, painful urination, insomnia, and convulsions. Clinical studies of the plant and the forskolin constituent support these traditional uses, but also indicate it may have therapeutic benefit in asthma, angina, psoriasis, and prevention of cancer metastases.

Asthma and Allergies

Coleus is an effective smooth muscle relaxer, resulting in bronchodilation, decreased airway resistance, increased vital capacity and increased forced expiratory volume. This action is the result of the increase in Cyclic AMP caused by coleus. Many asthma medications increase Cyclic AMP by inhibiting the enzymes that cause its breakdown. Thus, coleus and the traditional asthma drugs are likely to act synergistically. Therefore, one should consult their physician before combining them.

PINE BARK EXTRACT (Adult formulation only)

Pine bark extract, also known as Pycnogenol is a natural plant extract originating from the bark of the Maritime pine that grows along the coast of southwest France. It is an extremely potent antioxidant that has the potential to help the body get rid of destructive free radicals that can damage cells and cause health problems. Pycnogenol consists of phenolic acids, taxifolin and procyanidins. This extract is being widely studied for use in treating several different conditions. Pine bark extract has been widely studied for over 35 years to learn the different conditions that it might help with. It has been used in folk medicine around the world for hundreds of years. In fact, it has been widely speculated that a tea of pine bark and needles was served to early explorers who were suffering from the symptoms of scurvy over 450 years ago.

Anti-inflammatory

Specific conditions that may be benefitted by pine bark extract include varicose veins, allergies, asthma, high blood pressure and diabetes. The anti-inflammatory activity can help reduce muscle soreness and joint pain. Pycnogenol might also increase the production of nitric oxide from vascular endothelial cells by stimulating nitric oxide synthetase. This can lead to vasodilation and possibly reduce the potential for atherogenesis and thrombus formation.

VITAMIN D₃

What is Vitamin D?

Vitamin D (the ‘sunshine’ vitamin) is a group of fat-soluble secosteroids, the two major physiologically relevant forms of which are vitamin D₂ (Ergocalciferol) and vitamin D₃ (Cholecalciferol) of which D₃ is the most potent of the two. Vitamin D without a subscript refers to either D₂ or D₃ or both. Vitamin D₃ is produced in the skin of vertebrates after exposure to ultraviolet B light from the sun or artificial sources, and occurs naturally in a small range of foods. In some countries, staple foods such as milk, flour and margarine are artificially fortified with vitamin D, and it is also available as a supplement in pill form. Food sources such as fatty fish, eggs, and meat are rich in vitamin D and are often recommended for consumption to those suffering vitamin D deficiency Light-exposed mushrooms

Vitamin D is essential to a healthy immune system

Vitamin D helps the immune system to fight infections. With a near-optimum blood level of vitamin D, you can expect fewer colds, 'flu, and other unwelcome opportunist. Not only does Vitamin D enhance your immunity, but it inhibits the development of destructive auto-immune diseases such as diabetes, rheumatoid arthritis, lupus and multiple sclerosis. Vitamin D is a major inhibitor of cancer, and part of this effect may be attributed to the increased vigilance of the immune system.

PHYTOSYN 12™

What is Phytosyn?

Phytosyn is HolGoun’s signature blend comprising of various extracts to assist with aspects of prevention of illnesses.

Benefits of Phytosyn

• Anti-histamine and anti-inflammatory effects
• relieves allergy symptoms by preventing the activation of immune responder cells and by inducing apoptosis, or cellular suicide, in already activated immune responder cells
• kill allergy-activated T cells and neutrophils during allergic reactions without affecting the T cells or neutrophils in their resting state
• an increased absorption of nutrients
• plant-derived enzyme complex to increase digestion of substrates
• enhances the immune system

PHYTOSYN 14™

Phytosyn14™ is a unique blend of ingredients that aids with digestion and the elimination of toxins, thereby helping the body to maximise nutrient absorption.   Phytosyn14™ has specifically been developed for children with allergies.

Additional benefits of Phytosyn14™ include:

• Increasing absorption of nutrients
• Boosting the metabolism and burning more fats and calories
• Fighting allergies and inflammations
• Replenishing trace elements
• Improving digestion.